Non-Steroidal Anti- Inflammatory Drugs

Non-steroidal anti-inflammatory drugs (NSAIDs) are a medication class that gatherings together medications that diminish torment, diminish fever, and, in higher measurements, diminish irritation. Paracetamol (acetaminophen) is for the most part not considered an NSAID since it has just minimal calming action. It treats torment chiefly by blocking COX-2 for the most part in the focal sensory system, yet very little in whatever is left of the body.

Most NSAIDs repress the action of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) and in this manner the amalgamation of prostaglandins and thromboxanes. It is suspected that restraining COX-2 prompts the calming, pain to relieve and antipyretic impacts and that those NSAIDs additionally repressing COX-1, especially headache medicine, may cause gastrointestinal draining and ulcers in expansive measurements.