Lead optimization
Lead optimization is an operationally diverse stage of the drug discovery process in which the chemical structures of compounds or biologics are modified to improve target specificity and selectivity, plus pharmacodynamic, pharmacokinetic, and toxicological properties to produce a preclinical drug candidate. This process requires detailed characterization of lead compound series and lead biologics, including data related to toxicity, efficacy, stability, and bioavailability.
- Biotherapeutics
- Cheminformatics
- Fragment-based lead discovery
Related Conference of Lead optimization
August 25-26, 2025
25th International Conference on Medicinal Chemistry, Drug Discovery & Drug Delivery
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Lead optimization Conference Speakers
Recommended Sessions
- ADME- Drug Chemistry
- Advances in Medicinal Chemistry
- Analytical Chemistry
- Anatomy and Physiology
- Anesthesia
- Anti-Microbials and Antibiotics
- Biochemistry
- Biosimilars
- Cardiovascular pharmacology
- Chemogenomics
- Clinical Psychology
- Clinical Pharmacology
- Drug Validation
- Entrepreneurs Investment Meet
- Ethnopharmacology
- Genotoxicity
- Green Chemistry
- Inflammation and Immunity studies
- Lead optimization
- Molecular and Cellular Pharmacology
- Non-Steroidal Anti- Inflammatory Drugs
- Novel Drug Discovery & Drug Delivery
- Organic Chemistry & Inorganic Chemistry
- Pharmaceutical formulation & Packaging
- Pharmaceuticals & Nutraceuticals
- Pharmacokinetics and Pharmacodynamics
- Phytochemistry and Phytopharmaceuticals
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- Principles of Pharmacology
- Psychopharmacology & Neuropharmacology
- Radiation Oncology
- Toxicology and Xenobiotics
- Traditional Medicine
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