Genotoxicity


In genetics, genotoxicity explains the property of chemical agents that destruct the genetic information inside a cell triggering mutations, which may lead to cancer. While genotoxicity is usually confused with mutagenicity, all mutagens are genotoxic, but not all genotoxic substances are mutagenic. The differentiation can have direct or indirect effects on the DNA. the orientation of mutations, misjudged event activation, and direct DNA damage leading to mutations Cells prevent expression of the genotoxic mutation by either DNA repair or apoptosis; however, the damage might not always be determined leading to mutagenesis.



 


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