24^th International Conference on Medicinal Chemistry and Drug Design September 19-20, 2024 Paris, France

Track 1: Medicinal Chemistry

Medicinal chemistry is primarily concerned with the research, optimization, and design of chemical molecules. This field covers a wide range of topics, including the synthesis of prospective medications and studies into their interactions with biological targets in order to better understand the drug's medical effects, metabolism, and adverse effects. Applied medicinal chemistry encompasses synthetic chemistry, natural product chemistry, and computational chemistry in close collaboration with chemical biology, enzymology, and structural biology, all with the goal of developing new therapeutic medicines.

• Organometallic chemistry
• Applied chemical applications

Track 2: Drug Design and Development

Therapeutic development refers to the process of bringing a new drug molecule into clinical use. In its broadest sense, this encompasses all processes from the initial research phase of identifying. It is divided into four stages, each with its own significance: stage 1 discovery and development occurs in second stage preclinical research, stage 3 clinical development occurs in stage 4 Food and Drug Administration review. The ultimate goal of drug development is to bring a novel chemical to market with a proven therapeutic benefit.

• Therapeutic effect
• Clinical practice
• Preclinical research

Track 3: Analytical Chemistry

Analytical chemists work in the pharmaceutical industry for the duration of the entire process, from drug discovery to market, analyzing the physical and chemical properties of drug components and formulations as well as determining the quality and stability of drug products to guarantee the safety of the medication. Titrimetric, chromatographic, spectroscopic, electrophoretic, and electrochemical analysis, as well as their comparable methods, are only a few of the analytical techniques utilized in the pharmaceutical sector that are included in the review.

• Process Analytical Chemistry
• Instrumental Methods
• Chromatographic Technique

Track 4: Chromatography

Chromatography is a technique for separating mixture components. The mixture's individual components go through the stationary phase at different speeds, causing them to separate. We can achieve precise separation, analysis, and purification utilizing chromatographic techniques. In chromatography, there are two phases: 1) stationary phase and 2) mobile phase. There are five distinct chromatographic procedures. 1. Chromatography in Columns 2. Chromatography on paper Thin Layer Chromatography is a type of chromatography that uses a thin layer3.paper chromatography 4.GLC(Gas-Liquid Chromatography) or Just Gas Chromatography (GC) 5.High Performance Liquid chromatography.

• Gas Chromatography
• Thin-Layer Chromatography
• Paper Chromatography
• Liquid Chromatography  

Track 5: Pharmacodynamics and Pharmacokinetics

The study of the biochemical, physiologic, and molecular effects of medications on the body, including receptor binding (including receptor sensitivity), post-receptor effects, and chemical interactions, is known as pharmacodynamics. Animals, microbes, and mixtures of species can all show signs of the outcomes. Pharmacodynamics is a term used to explain what a medicine does to the body. Pharmacodynamics is a pharmacology branch.

Pharmacokinetics, abbreviated as PK, is a discipline of pharmacology concerned with determining the fate of drugs given to a living organism. It is described as the study of a drug's absorption, distribution, metabolism, and excretion over time. The application of pharmacokinetic concepts to the safe and effective therapeutic administration of medications in a private patient is known as clinical pharmacokinetics. It can be put to use.

• Drug safety and efficiency
• Biochemical interactions
• Pharmacology
• Therapeutic
• Kinetics of drug disposition
• Clinical Pharmacokinetics

Track 6: Medicinal Chemistry for Drug Discovery

Medicinal chemists are critical to the success of a drug development effort, relying on their knowledge and skill in current organic chemistry, disease biology, in vitro and in vivo pharmacological screening, and pharmacokinetic features to maximize efficacy while decreasing size. The process of selecting and synthesizing compounds that establish structure–activity correlations and achieve efficacy and safety in preclinical animal testing is aided by medicinal chemistry.

• Pharmacological Screening
• Pharmacokinetics
• Structure activity

Track 7: Organic and Inorganic Chemistry

Organic chemistry is important in the pharmaceutical business because it helps to illuminate research and advance the discovery, research, and development of new medications by providing knowledge about organic substances. In nature, drugs, and technology, organic molecules play an important role. It serves as the brain of the system, allowing it to comprehend structure and responsiveness. Organic chemists continue to play an important part in the drug discovery process in the pharmaceutical sector. Metal ions are important in biological processes and the study of Inorganic chemistry. Inorganic chemicals that are employed as medicines and diagnostic agents for the treatment of manic-depressive illnesses, lithium medications such as lithium carbonate Li2C03! Are employed. Cisplatin works in a unique way.

• Hydrocarbons
• Pharmaceutical Industry
• Coordination Chemistry
• Bio organometallic chemistry
• Material chemistry

Track 8: Antibiotics

Antibiotics are drugs that help people and animals combat bacterial illnesses. Antibiotics are antibacterial in nature. Antibiotic drugs are widely employed in the treatment and prevention of bacterial infections, and they are the most important type of antibacterial agent available. Antiprotozoal action is seen in a small number of antibiotics. Penicillin, ampicillin, cephalexin, ciprofloxacin, azithromycin, and erythromycin are among the most regularly used antibiotics. Protozoan infections are frequently treated with antibiotics. (Metronidazole can be used to treat a variety of parasitic infections.) Antibiotics can either kill or stop germs from growing.

• Mold-derived biological antibiotics
• Antibiotics generated from dyes are synthetic antibiotics.
• RNA tumor viruses control oncogenic events chemically

Track 9: Drug Chemistry

Medicinal chemistry is the branch of science concerned with the discovery or creation of new therapeutic compounds and their subsequent development into usable medicines. It could include the creation of novel compounds, as well as research on the relationships between the structures of natural and manufactured chemicals.

• Production of pharmaceutical
• Drug distribution
• Data management and analysis
• Quality Assurance and Testing
• ADME (Absorption, Distribution, Metabolism and Excretion) of drugs.

Track10:  Vaccine and Drug Delivery System

Medicinal chemistry is concerned with the development of useful medications and the design of new medicinal compounds. It focuses on small organic compounds, which includes synthetic organic chemistry, computational chemistry, and natural product features. This field of study combines chemical biology, enzymology, and structural biology to pave the path for the discovery and development of new therapeutics. Chemical entities are suited for therapeutic usage after identification of chemical features and then systematic and synthetic change.

• Formulations
• Immunotherapy and Vaccines
• Human Vaccines
• Cancer Vaccines
• Vaccination risk factor

Track 11: Biochemistry

Biochemistry is the study of chemical processes and transformations that take place at the molecular level in living organisms. Among the scientific topics covered are genetics, microbiology, forensics, plant science, and medicine. It's a discipline of biology that delves into the structure, function, metabolism, and processes of cell constituents including proteins, carbohydrates, lipids, and nucleic acids, all the way down to the molecular level. After investigating the transport of soluble chemicals in cells that allowed for day-to-day cellular functions, Carl Newberg, a pioneer of biochemistry, coined the term in 1903. Biochemistry is the study of biological functions at the cellular and molecular level utilizing chemicals. Scientists combined chemistry, physiology, and biology to explore the human body around the turn of the twentieth century.

• Proteins and membranes.
• Disease mechanisms.
• Metabolism.
• Structure and function of molecules

Track 12: Spectroscopy

In drug discovery investigations, many spectroscopic methods are used. Several mass spectrometric techniques, including Accelerator Mass Spectrometry, are being used in early drug discovery, preclinical and clinical research, as well as Phase 0 trials. Life scientists are increasingly relying on technologies such as HPLC, HPTLC, and LC-MS to study minute entities as well as larger molecules. Mass Spectrometry with liquid chromatography (LC-MS). High performance liquid chromatography (HPLC)-MS is a systematic approach that combines high resolution chromatographic separation with sensitive and selective mass spectrometric detection. It is, without a doubt, the most effective method for pharmaceutical analysis. In pharmaceutical analysis, LC-MS has been used for drug metabolism research, as well as the study and detection of contaminants and degradation products in pharmaceuticals.

• Drug discovery using mass spectroscopy
• Applications of nmr spectroscopy in drug discovery

Track13: Biomarkers in Drug Design

Indian Society for Clinical Organization, Tech Association of British Pharmaceutical Industry Researchers have been able to find an increasing number of critical molecular drivers of cancer growth thanks to advances in cancer molecular characterization. These drug discoveries have resulted in a number of novel anticancer therapies as well as scientific advancement in specific patient populations. Despite this, the identification of clinically meaningful response biomarkers is still a work in progress. We discuss methodologies for cancer molecular characterization and the role of biomarkers in the development of innovative anticancer treatments in this review.

Any new biomarkers discovered and evaluated should preferably adhere to the Clinical Laboratory Improvement Amendments (CLIA) and Good Clinical Laboratory Practice (GCLP) standards.

• Oncology and Infectious Diseases Medicine Development
• Drug Discovery Innovation and Strategies
• Drug discovery using computational chemistry and informatics

Track14: Pharmaceutical Marketing

The business of promoting or advertising the sale of pharmaceutical medications is known as pharmaceutical marketing. It's also known as pharmaceutical marketing or medico marketing. Pharmaceutical marketing aids in the promotion of chronic disease treatments. Growing hazards, rising prices, changing consumer needs, and stricter regulations are the primary contributing variables to consider in Parma marketing. According to the World Health Organization, the worldwide pharmaceutical business was worth $300 billion in 2015.

 Track15: NMR Role in Rational Drug Design

The discovery of drugs and the process by which they are developed both heavily rely on NMR spectroscopy. In order to find high-affinity ligands for biologically significant macromolecules, elucidate ligand-binding sites, and identify small molecules with a wide range of binding affinities, NMR screening experiments are very efficient and versatile. As a result, they are proving to be a useful and reliable tool in the structure-based drug design process. As it can illuminate the molecular structure of the biomolecules, explain and validate the structure of the drugs, and provide structural details on the interaction of the biomolecules (target) with small molecule compounds, it is very effective in the discovery and development of new drugs. As a result, NMR spectroscopy is a great tool for pharmaceutical research

Track16: Food Chemistry

As its name suggests, the field of chemistry known as food chemistry studies the biochemistry of food, including its characteristics and physiological activities. Organic chemistry is the study of the composition, production, reactions, and properties of molecules containing carbon. Though they may also contain a number of additional  elements, the majority of organic molecules are made up of carbon and hydrogen.

It explains the alterations that take place to food while cooking and storing. Food chemistry is a scientific field that primarily focuses on the chemical makeup of foods, basic biomolecules, the chemical structure and characteristics of food ingredients, chemical changes that occur in foods during processing and storage, and methods to detect and control food spoilage.

The medicinal chemistry for drug discovery market is expected to experience significant growth from 2022 to 2029. According to an analysis by Data Bridge Market Research, the market is projected to reach USD 12,173.97 million by 2029, with a compound annual growth rate (CAGR) of 13.5% during this period. The increasing prevalence of chronic diseases and the expansion of biologics are the primary drivers of this market's growth.

Medicinal chemistry is a collaborative field that brings together synthetic organic chemists, analytical chemists, biologists, toxicologists, pharmacologists, microbiologists, and biopharmacists. These interdisciplinary teams work together to discover new drugs, develop innovative pharmaceuticals, and improve existing ones. Medicinal chemistry plays a critical role throughout the entire clinical development process, not just in the discovery phase. During clinical trials, large quantities of drug formulations are utilized at each stage to evaluate potential benefits for human health.

Advancements in chemical processes used for compound discovery have driven the development of technologies such as combinatorial chemistry (combichem), microwave-assisted organic synthesis (MAOS), and high-throughput (HTS) biological screening, which have revolutionized the field of medicinal chemistry.